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DR RV ANAND CONSULTANT NEUROLOGIST SAI NEURO CLINIC MANDAVELI PARKINSON DISEASE LOSS OF SENSE OF SMELL happens early in the course of illness, even before more familiar symptoms appear.often patients do not notice it.difficulty identifying odours and discriminating them have been identified PAIN pain ful sensations are fairly commonly reported in parkinson disease.it can be piercing or stabbing, burning or tingling. it may be felt in several areas of the body.it corresponds to the body parts affected by motor symptoms.it is more promminent as medication effect wears off